Dataset:21980333 Search Result
Clinical Information
Clinical, demographic and laboratory characteristics of hospitalized patients with pandemic influenza A/H1N1/2009 virus infection.
Characteristic Patients with viral RNA detected in respiratory samples only (n = 119) Patients with viral RNA detected in blood samples (n = 14) p
Demographics and co-morbidities
Age, in median years (range) 47 (18–85) 49 (19–59) 0.689
Sex
 Male 62 (52.1%) 7 (50.0%) 1
 Female 57 (47.9%) 7 (50.0%)
Underlying illness 85 (71.4%) 11 (78.6%) 0.757
Pregnancy (in women of childbearing age) 5 / 35 (13.3%) 0 / 4 (0.0%) 1
Laboratory findings on admission (median and range)
Total leucocyte count, ×109 cells/L 7.2 (0.8–32.05)* 4.4 (1.5–9) 0.0033
Neutrophil count, ×109 cells/L 5.3 (0.33–30.45)† 3.1 (1.1–7.3)‡ 0.0271
Lymphocyte count, ×109 cells/L 0.8 (0.2–2.8)† 0.37 (0.1–1)‡ 0.0004
Platelet count, ×109 platelets/L 196 (13–400)* 152 (81–267) 0.0308
Alanine transaminase level, IU/L 20 (<6–261)§ 58 (13–343) 0.0001
Clinical severity
Severe 67 (56.3%) 14 (100%) 0.0025
Mild 52 (43.7%) 0 (0.0%)
Clinical outcome (all cases)
Survived 103 (86.6%) 8 (57.1%) 0.013
Died 16 (13.4%) 6 (42.9%)
Clinical outcome (severe cases only)
Survived 50 (75.8%) 8 (57.1%) 0.192
Died 16 (24.2%) 6 (42.9%)  
Patients with viral RNA detected in stool/ rectal samples but not blood (n = 6) were excluded from the comparison.
*(n = 117);
†(n = 113);
‡(n = 11);
§(n = 115).