Dataset:32706371 Search Result
Clinical information
Demographic, Clinical, Laboratory, and Radiographic Findings of Investigated Patients
	Family 1		Family 2		Reference ranges
	II-1	II-2	II-1	II-2
Demographic characteristics
Age, y	32	29	21	23
Sex	Male	Male	Male	Male
Medical history	Nonallergic rhinitis	None	None	Malaria infection
Clinical characteristics at presentation
Time from symptom onset to hospitalization, d	8	3	10	7-9
Symptoms at disease onset	Dyspnea, productive cough, fever	Cough, fever, myalgia, headache	Cough, fever, nausea, vomiting	Dyspnea, cough, fever, vomiting, myalgia
Imaging features (CT scan)	Bilateral ground-glass opacities with dense infiltrates	Bilateral pulmonary consolidations	Bilateral pulmonary consolidations	Bilateral pulmonary consolidations
ICU admission
Time from symptom onset to ICU admission, d	8	6	10	11
Medical reason for ICU admission	Respiratory insufficiency	Respiratory insufficiency	Elevated right-sided heart pressure, respiratory insufficiency	Respiratory insufficiency
Disease severity status on admission, SOFA scorea	2	5	2	4
Laboratory findings at ICU admission
Chemistry
Alanine aminotransferase, U/L	28	30	31	37	<45
Albumin, g/L	24.2	26	23	20	35-50
Alkaline phosphatase, U/L	79	103	86	81	40-125
Aspartate aminotransferase, U/L	33	36	36	39	<35
Cardiac troponin, high sensitivity, pg/mL	<3	6	<10	NA	<3
Creatine kinase, U/L	102	32	52	82	<170
Creatinine, μmol/L	85	73	49	50	60-110
eGFR, mL/min/1.73 m2	105	119	>90	>90	>90
γ-Glutamyltransferase, U/L	19	275	127	101	<55
Lactate dehydrogenase, U/L	357	275	373	365	<250
Blood count
Hemoglobin, mmol/L	8.2	8.3	8.2	7.1	8.5-11.0
Lymphocyte count, ×109/L	2.1	1.3	0.6	0.9	1.0-3.5
White blood cell count, ×109/L	17	11.8	14.7	9	4.0-10.0
Platelet count, ×109/L	309	369	220	287	150-400
Coagulation
Activated partial thromboplastin time, s	NA	NA	29	21	26-34
D-dimer, ng/mL	NA	490	660	NA	<500
Fibrinogen, g/L	NA	9.9	NA	NA	1.6-3.2
Prothrombin time, s	NA	NA	12.6	NA	12-15
Inflammatory markers
C-reactive protein, mg/L	343	444	>500	222	<10
Ferritin, μg/L	NA	1119	1130	NA	20-300
Procalcitonin, μg/L	NA	1.28	NA	NA	<0.5
Secondary complications	Left-sided pneumothorax with giant bullae, signs of fibrosis on CT scan	Persistently high fever and vasopressor-refractory distributive shock, concurrent bacterial superinfection, leading to death	Subsegmental pulmonary embolism	None reported
Duration of viral shedding after COVID-19 onset (positive SARS-CoV-2 PCR), d	Positive at admission, no follow-up measurement	12	13	Positive at admission, no follow-up measurement
Duration of ventilatory support, d	9	10	11	9
Duration of ICU stay, d	16	10 (Deceased)	16	10
Follow-up
Time from ICU discharge to hospital discharge, d	17		6	6
Complications during follow-up period	Readmission due to secondary right-sided pneumothorax		None reported	None reported