| Dataset:32986807 Search Result | ||||||||
| Clinical information | ||||||||
| Clinical and Biological Variables Before and After Remdesivir and Convalescent Plasma Treatment | ||||||||
| Variables | Baseline, 12 April | Remdesivir, d0 27 May | Remdesivir, d5 31 May | CP, d0 12 June | CP, d10 22 June | CP, d16 28 June | CP, d30 13 July | CP, d80 1 September |
| Oxygen | Room air | 3 L/min | 1.5 L/min | 1 L/min | Room air | Room air | Room air | Room air |
| Saturation, % | 93 | 94 | 98 | 94 | 95 | 95 | 96 | 96 |
| Temperature max., °C | 38.5 | 38.9 | 37.1 | 38.8 | 36.5 | 37.1 | 36.9 | 37.8 |
| C-reactive protein, mg/L | 14 | 137 | 38 | 77 | 1 | 1 | 1 | 2 |
| Platelets, g/L | 92 | 86 | 161 | 88 | 144 | 140 | 167 | 131 |
| Leukocytes, g/L | 0.810 | 3.04 | 2.44 | 4.7 | 3.98 | 4.5 | 2.94 | 3.31 |
| Lymphocytes, g/L | 0.1 | 0.06 | 0.17 | 0.13 | 0.32 | 0.34 | 0.28 | 0.37 |
| Date(s) of sampling | 12 April, 24 April, 27 April | 15 May, 27 May | 31 May | 9 June | 16 June | 28 June | 13 July | 1 September |
| Nature of sample | Nasop/Nasop/ bronchoalveolar lavage | Nasop | Nasop | Nasop | Nasop | Nasop | Nasop | Nasop |
| Reverse-transcription polymerase chain reaction result (method) | +(Cep)/+(Pas) | +(Cep)/+(Pas) | +(Cep) | +(Pas) | +(Pas) | +(Pas) | −(Pas) | −(Pas) |
| Cycle threshold | NA/23 | NA/21 | NA | 21 | 25 | 28 | NA | NA |
| Blood viremia (plasma EDTA) | NA | May 27 | NA | 9 June, 12 June | 16 June, 22 June | 22 June | 13 July | 1 September |
| Log10 copies/mL | 3.88 | 3.94/3.84 | Not detected | Not detected | Not detected | Not detected | ||
| Anti–severe acute respiratory syndrome coronavirus 2 antibodiesa (optical density index ratio) | NA | … | NA | NA | +5.97 | NA | NA | + 0.92 |
| Remdesivir (d0 = 27 May d5= 31 May) and CP (d0 = 12 June d10 = 22 June, d16 = 28 June, d30 13 July and d80 = 1 September). | ||||||||
| Abbreviations: Cep, Cepheid; CP, convalescent plasma; NA, not available; Nasop, nasopharynx, Pas: Pasteur. | ||||||||
| aImmunochemiluminescence Roche Cobas 6000 (threshold 0.9–1.10). | ||||||||