AVM

Protein name	Nucleocapsid Phosphoprotein
Uniprot protein ID	P0DTC9
Protein length	419 amino acids
Protein description	The Nucleocapsid Phosphoprotein has a modular organization which can be divided into intrinsically disordered regions (IDRs) and conserved structural regions according to the sequence characteristics. The IDRs include three modules: N-arm, central Ser/Arg-rich flexible linker region (LKR), and C-tail, while the conserved structural regions including two modules: N-terminal domain (NTD) and C-terminal domain (CTD). In the primary structure, NTD and CTD are connected by LKR and are usually flanked by N-arm and C-tail. The nucleocapsid phosphoprotein is a structural protein that binds to, protects the viral RNA genome and is involved in packaging the RNA into virus particles. The N protein has been suggested as an antiviral drug target.

Pubmed ID	33368386
Clinical information	No
Disease	-
Published year	2021
Journal	JOURNAL OF MEDICAL VIROLOGY
Title	Dynamic tracking of variant frequencies depicts the evolution of mutation sites amongst SARS-CoV-2 genomes from India
Author	Shenu Hudson B,Vaishnavi Kolte,Azra Khan,Gaurav Sharma
Evidence	The mutational probabilities of these 118 sites across all time points (month-wise) were visualized using a clustered heatmap where six clusters were obtained with 4, 3, 2, 5, 5, and 99 sites per cluster (Figure 1A,B and Table S2).