Mutation detail:
| Mutation site | M117V |
| Virus | Human rhinovirus |
| Mutation level |
Amino acid level |
| Gene/protein/region type | VP3 |
| Gene ID | 5758809 |
| Country | - |
| Mutation type |
nonsynonymous mutation |
| Genotype/subtype/clade | C |
| Sample |
cell line |
| Variants | - |
| Viral reference sequence | GU219984.1 |
| Drug/antibody/vaccine | - |
| Transmissibility |
- |
| Transmission mechanism | - |
| Pathogenicity |
- |
| Pathogenicity mechanism | - |
| Immune escape mutation | - |
| Immune escape mechanism | - |
| RT-PCR primers probes | - |
Protein detail:
| Protein name | Capsid Protein VP3 |
| Uniprot protein ID | A0A2P1DXU1 |
| Protein length | 235 amino acids |
| Protein description | Capsid protein VP3 forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. |
Literature information:
| Pubmed ID | 27743961 |
| Clinical information | No |
| Disease | - |
| Published year | 2016 |
| Journal | Virology |
| Title | Mutations in VP1 and 3A proteins improve binding and replication of rhinovirus C15 in HeLa-E8 cells |
| Author | Yury A Bochkov,Kelly Watters,Sarmila Basnet,Shakher Sijapati,Marchel Hill |
| Evidence | Figure2 |