AVM v1, released 02-OCT-22

A manually curated database of aerosol-transmitted virus mutations, human diseases, and drugs

Mutation detail:


Mutation site 69424G>A
Virus Varicella-Zoster virus
Mutation level Nucleotide level
Gene/protein/region type ORF38
Gene ID 1487706
Country Canada
Mutation type -
Genotype/subtype/clade -
Sample Human
Variants -
Viral reference sequence NC_001348.1
Drug/antibody/vaccine -
Transmissibility -
Transmission mechanism -
Pathogenicity -
Pathogenicity mechanism -
Immune escape mutation -
Immune escape mechanism -
RT-PCR primers probes -

Protein detail:


Protein name Tegument Protein UL21
Uniprot protein ID Q4JQT7
Protein length 541 amino acids
Protein description Tegument Protein UL21 may participate in DNA packaging/capsid maturation events. Promotes efficient incorporation of tegument proteins UL46, UL49, and US3 homologs into virions. May also play a role in capsid transport to the trans-Golgi network (TGN).

Literature information:


Pubmed ID 22837206
Clinical information No
Disease -
Published year 2012
Journal JOURNAL OF VIROLOGY
Title The Attenuated Genotype of Varicella-Zoster Virus Includes an ORF0 Transitional Stop Codon Mutation
Author Geoffrey A Peters,Shaun D Tyler,John E Carpenter,Wallen Jackson,Yasuko Mori
Evidence Table1