Mutation detail:
| Mutation site | E34D |
| Virus | Norovirus |
Mutation level  |
Amino acid level |
| Gene/protein/region type | ORF3 |
| Gene ID | 1491971 |
| Country | Japan |
| Mutation type |
nonsynonymous mutation |
| Genotype/subtype/clade | GII.4 |
| Sample |
Human |
| Variants | - |
| Viral reference sequence | X86557.1 |
| Drug/antibody/vaccine | - |
| Transmissibility |
- |
| Transmission mechanism | - |
| Pathogenicity |
- |
| Pathogenicity mechanism | - |
| Immune escape mutation | - |
| Immune escape mechanism | - |
| RT-PCR primers probes | - |
Protein detail:
| Protein name | Protein VP2 |
| Uniprot protein ID | Q83885 |
| Protein length | 212 amino acids |
| Protein description | The ORF3 encodes the minor capsid protein VP2, minor structural protein present in one or two copies per virion. VP2 stabilizes capsid protein VP1 by protecting it from disassembly and degradation. VP2 may play a role in RNA genome packaging. |
Literature information:
| Pubmed ID | 18768979 |
| Clinical information | No |
| Disease | - |
| Published year | 2008 |
| Journal | Journal of Virology |
| Title | Identification of monomorphic and divergent haplotypes in the 2006-2007 norovirus GII/4 epidemic population by genomewide tracing of evolutionary history |
| Author | Kazushi Motomura, Tomoichiro Oka, Masaru Yokoyama, Hiromi Nakamura, Hiromi Mori |
| Evidence | FIG.4 |