Mutation detail:
| Mutation site | Q261R |
| Virus | Human rhinovirus |
Mutation level  |
Amino acid level |
| Gene/protein/region type | P2-C |
| Gene ID | 1493933 |
| Country | - |
| Mutation type |
nonsynonymous mutation |
| Genotype/subtype/clade | A |
| Sample |
cell line |
| Variants | - |
| Viral reference sequence | KX891411.1 |
| Drug/antibody/vaccine | - |
| Transmissibility |
- |
| Transmission mechanism | - |
| Pathogenicity |
- |
| Pathogenicity mechanism | - |
| Immune escape mutation | - |
| Immune escape mechanism | - |
| RT-PCR primers probes | - |
Protein detail:
| Protein name | P2-C Polypeptide |
| Uniprot protein ID | P07210 |
| Protein length | 321 amino acids |
| Protein description | P2-C induces and associates with structural rearrangements of intracellular membranes. P2-C displays RNA-binding, nucleotide binding and NTPase activities. May play a role in virion morphogenesis and viral RNA encapsidation by interacting with the capsid protein VP3. |
Literature information:
| Pubmed ID | 27743961 |
| Clinical information | No |
| Disease | - |
| Published year | 2016 |
| Journal | Virology |
| Title | Mutations in VP1 and 3A proteins improve binding and replication of rhinovirus C15 in HeLa-E8 cells |
| Author | Yury A Bochkov,Kelly Watters,Sarmila Basnet,Shakher Sijapati,Marchel Hill |
| Evidence | Figure6 |