AVM v1, released 02-OCT-22

A manually curated database of aerosol-transmitted virus mutations, human diseases, and drugs

Mutation detail:


Mutation site F91S
Virus Norovirus
Mutation level Amino acid level
Gene/protein/region type ORF3
Gene ID 1491971
Country China
Mutation type nonsynonymous mutation
Genotype/subtype/clade GII.4
Sample Human
Variants -
Viral reference sequence JN595867.1
Drug/antibody/vaccine -
Transmissibility -
Transmission mechanism -
Pathogenicity -
Pathogenicity mechanism -
Immune escape mutation -
Immune escape mechanism -
RT-PCR primers probes -

Protein detail:


Protein name Protein VP2
Uniprot protein ID Q83885
Protein length 212 amino acids
Protein description The ORF3 encodes the minor capsid protein VP2, minor structural protein present in one or two copies per virion. VP2 stabilizes capsid protein VP1 by protecting it from disassembly and degradation. VP2 may play a role in RNA genome packaging.

Literature information:


Pubmed ID 23824633
Clinical information No
Disease -
Published year 2013
Journal Virus Genes
Title Complete genome analysis of a novel norovirus GII.4 variant identified in China
Author Liang Xue, Qingping Wu, Xiaoxia Kou, Weicheng Cai, Jumei Zhang
Evidence Table 1