AVM v1, released 02-OCT-22

A manually curated database of aerosol-transmitted virus mutations, human diseases, and drugs

Mutation detail:


Mutation site 95241T>G
Virus Varicella-Zoster virus
Mutation level Nucleotide level
Gene/protein/region type ORF54
Gene ID 1487723
Country Ireland
Mutation type -
Genotype/subtype/clade -
Sample Human
Variants -
Viral reference sequence X04370.1
Drug/antibody/vaccine -
Transmissibility -
Transmission mechanism -
Pathogenicity -
Pathogenicity mechanism -
Immune escape mutation -
Immune escape mechanism -
RT-PCR primers probes -

Protein detail:


Protein name Capsid Portal Protein
Uniprot protein ID P09302
Protein length 769 amino acids
Protein description Forms a portal in the viral capsid through which viral DNA is translocated during DNA packaging. Assembles as a dodecamer at a single fivefold axe of the T=16 icosahedric capsid. Binds to the molecular motor that translocates the viral DNA, termed terminase.

Literature information:


Pubmed ID 15042660
Clinical information No
Disease -
Published year 2004
Journal Journal of Medical Virology
Title Genetic Variation in Clinical Varicella-Zoster Virus Isolates Collected in Ireland Between 2002 and 2003
Author Michael J. Carr,1 Grace P. McCormack,2 and Brendan Crowley
Evidence Table3