AVM v1, released 02-OCT-22

A manually curated database of aerosol-transmitted virus mutations, human diseases, and drugs

Mutation detail:


Mutation site 78385C>T
Virus Varicella-Zoster virus
Mutation level Nucleotide level
Gene/protein/region type ORF43
Gene ID 1487670
Country Canada
Mutation type -
Genotype/subtype/clade -
Sample Human
Variants -
Viral reference sequence NC_001348.1
Drug/antibody/vaccine -
Transmissibility -
Transmission mechanism -
Pathogenicity -
Pathogenicity mechanism -
Immune escape mutation -
Immune escape mechanism -
RT-PCR primers probes -

Protein detail:


Protein name DNA packaging tegument protein UL17
Uniprot protein ID P09292
Protein length 676 amino acids
Protein description DNA packaging tegument protein UL17 plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.

Literature information:


Pubmed ID 22837206
Clinical information No
Disease -
Published year 2012
Journal JOURNAL OF VIROLOGY
Title The Attenuated Genotype of Varicella-Zoster Virus Includes an ORF0 Transitional Stop Codon Mutation
Author Geoffrey A Peters,Shaun D Tyler,John E Carpenter,Wallen Jackson,Yasuko Mori
Evidence Table1