AVM v1, released 02-OCT-22

A manually curated database of aerosol-transmitted virus mutations, human diseases, and drugs

Mutation detail:


Mutation site D72G
Virus SARS-CoV-2
Mutation level Amino acid level
Gene/protein/region type E
Gene ID 43740570
Country -
Mutation type nonsynonymous mutation
Genotype/subtype/clade -
Sample Human
Variants -
Viral reference sequence NC_045512.2
Drug/antibody/vaccine -
Transmissibility -
Transmission mechanism -
Pathogenicity -
Pathogenicity mechanism -
Immune escape mutation -
Immune escape mechanism -
RT-PCR primers probes -

Protein detail:


Protein name Envelope Protein
Uniprot protein ID P0DTC4
Protein length 75 amino acids
Protein description The SARS-CoV-2 envelope (E) protein is a small structural protein involved in many aspects of the viral life cycle. The E protein promotes the packaging and reproduction of the virus, and deletion of this protein weakens or even abolishes the virulence.

Literature information:


Pubmed ID 33347622
Clinical information No
Disease -
Published year 2021
Journal JOURNAL OF VIROLOGY
Title Comparative insight into the genomic landscape of SARS-CoV-2 and identification of mutations associated with the origin of infection and diversity
Author Divya Mishra, Gurparsad Singh Suri, Gurleen Kaur, Manish Tiwari
Evidence The analyses of 2325 severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genomes revealed 107, 162, and 65 nucleotide substitutions in the coding region of SARS-CoV-2 from the three continents America, Europe, and Asia, respectively. Figure6,Figure7,Figure8.