Mutation detail:
| Mutation site | D80Y |
| Virus | SARS-CoV-2 |
Mutation level  |
Amino acid level |
| Gene/protein/region type | S |
| Gene ID | 43740568 |
| Country | UK, USA, Canada, France, Switzerland, Germany, Norway, Italy, Denmark, Australia, Japan, Belgium, Netherlands, Turkey, Russian Federation, India, Kenya, Portugal, Spain, Indonesia, Rwanda, Austria, Ireland, Croatia, Romania, Mexico, South Africa, Israel, |
| Mutation type |
nonsynonymous mutation |
| Genotype/subtype/clade | - |
| Sample |
Human |
| Variants | - |
| Viral reference sequence | NC_045512.2 |
| Drug/antibody/vaccine | - |
| Transmissibility |
- |
| Transmission mechanism | - |
| Pathogenicity |
- |
| Pathogenicity mechanism | - |
| Immune escape mutation | - |
| Immune escape mechanism | - |
| RT-PCR primers probes | - |
Protein detail:
| Protein name | Spike glycoprotein |
| Uniprot protein ID | P0DTC2 |
| Protein length | 1273 amino acids |
| Protein description | Spike protein is one of the structural proteins of SARS-CoV-2. The monomeric protein consists of one large ectodomain, a single-pass transmembrane anchor, and a short intracellular tail at C-terminus. It encompasses 22 glycosylation sites. S protein cleaves into two subunits namely S1 and S2 following receptor recognition. Receptor Binding Domain (RBD) in S1 subunit plays a major role in ACE2 receptor binding. |
Literature information:
| Pubmed ID | 33568759 |
| Clinical information | No |
| Disease | - |
| Published year | 2021 |
| Journal | Scientific Reports |
| Title | Genomic mutations and changes in protein secondary structure and solvent accessibility of SARS-CoV-2 (COVID-19 virus) |
| Author | Thanh Thi Nguyen,Pubudu N. Pathirana,Thin Nguyen,Quoc Viet Hung Nguyen,Asim Bhatti |
| Evidence | Based on 6324 viral genome sequences, we create a spreadsheet dataset of point mutations that can facilitate the investigation of SARS-CoV-2 in many perspectives, especially in tracing the evolution and worldwide spread of the virus. |