Mutation detail:
Mutation site | V33L |
Virus | Human rhinovirus |
Mutation level ![]() |
Amino acid level |
Gene/protein/region type | VP2 |
Gene ID | 1461213 |
Country | - |
Mutation type ![]() |
nonsynonymous mutation |
Genotype/subtype/clade | B |
Sample ![]() |
cell line |
Variants | - |
Viral reference sequence | NC_001490.1 |
Drug/antibody/vaccine | LPCRW_0005 resisitant |
Transmissibility ![]() |
- |
Transmission mechanism | - |
Pathogenicity ![]() |
- |
Pathogenicity mechanism | - |
Immune escape mutation | - |
Immune escape mechanism | - |
RT-PCR primers probes | - |
Protein detail:
Protein name | Capsid Protein VP2 |
Uniprot protein ID | P03303 |
Protein length | 262 amino acids |
Protein description | VP2 forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. |
Literature information:
Pubmed ID | 24948704 |
Clinical information | No |
Disease | - |
Published year | 2014 |
Journal | Journal Of Antimicrobial Chemotherapy |
Title | A novel benzonitrile analogue inhibits rhinovirus replication |
Author | Celine Lacroix,Jordi Querol-Audi,Manon Roche,David Franco,Mathy Froeyen |
Evidence | an additional V33L mutation was detected in VP2. |