Mutation detail:
Protein detail:
| Protein name | ORF7b |
| Uniprot protein ID | - |
| Protein length | 43 amino acids |
| Protein description | ORF7b encodes a viral accessory protein. Based on its similarity to other coronavirus proteins, ORF7b protein is thought to localize to the Golgi compartment. The orf7b is a hydrophobic protein with a transmembrane domain N-terminal at the outside, and a cytoplasmic C-terminal. Similar to orf7a, orf7b is reported by the majority of the previous studies that it is not essential for virus replication. |
Literature information:
| Pubmed ID | 34044192 |
| Clinical information | No |
| Disease | - |
| Published year | 2021 |
| Journal | INFECTION GENETICS AND EVOLUTION |
| Title | E484K as an innovative phylogenetic event for viral evolution: Genomic analysis of the E484K spike mutation in SARS-CoV-2 lineages from Brazil |
| Author | Patrícia Aline Grohs Ferrareze, Vinicius Bonetti Franceschi, Amanda de Menezes Mayer, Gabriel Dickin Caldana, Ricardo Ariel Zimerman |
| Evidence | A hallmark of these Brazilian lineages is the presence of multiple lineage-defining mutations per lineage (Table 1 ). |