Mutation detail:
| Mutation site | E3stop |
| Virus | SARS-CoV-2 |
Mutation level  |
Amino acid level |
| Gene/protein/region type | ORF7b |
| Gene ID | 43740574 |
| Country | - |
| Mutation type |
nonsynonymous mutation |
| Genotype/subtype/clade | - |
| Sample |
Human |
| Variants | Omicron |
| Viral reference sequence | NC_045512.2 |
| Drug/antibody/vaccine | - |
| Transmissibility |
- |
| Transmission mechanism | - |
| Pathogenicity |
- |
| Pathogenicity mechanism | - |
| Immune escape mutation | - |
| Immune escape mechanism | - |
| RT-PCR primers probes | - |
Protein detail:
| Protein name | ORF7b |
| Uniprot protein ID | - |
| Protein length | 43 amino acids |
| Protein description | ORF7b encodes a viral accessory protein. Based on its similarity to other coronavirus proteins, ORF7b protein is thought to localize to the Golgi compartment. The orf7b is a hydrophobic protein with a transmembrane domain N-terminal at the outside, and a cytoplasmic C-terminal. Similar to orf7a, orf7b is reported by the majority of the previous studies that it is not essential for virus replication. |
Literature information:
| Pubmed ID | 35367284 |
| Clinical information | No |
| Disease | - |
| Published year | 2022 |
| Journal | Virus Research |
| Title | Mutational cascade of SARS-CoV-2 leading to evolution and emergence of omicron variant |
| Author | Yusha Araf, Fariya Akter, Yan-Dong Tang, Rabeya Fatemi, Md Sorwer Alam Parvez |
| Evidence | Table 3 |