AVM v1, released 02-OCT-22

A manually curated database of aerosol-transmitted virus mutations, human diseases, and drugs

Mutation detail:


Mutation site E8D
Virus SARS-CoV-2
Mutation level Amino acid level
Gene/protein/region type E
Gene ID 43740570
Country Bangladesh
Mutation type nonsynonymous mutation
Genotype/subtype/clade -
Sample Human
Variants -
Viral reference sequence NC_045512.2
Drug/antibody/vaccine -
Transmissibility -
Transmission mechanism -
Pathogenicity -
Pathogenicity mechanism -
Immune escape mutation -
Immune escape mechanism -
RT-PCR primers probes -

Protein detail:


Protein name Envelope Protein
Uniprot protein ID P0DTC4
Protein length 75 amino acids
Protein description The SARS-CoV-2 envelope (E) protein is a small structural protein involved in many aspects of the viral life cycle. The E protein promotes the packaging and reproduction of the virus, and deletion of this protein weakens or even abolishes the virulence.

Literature information:


Pubmed ID 34251592
Clinical information No
Disease -
Published year 2021
Journal VIRUS GENES
Title Temporal landscape of mutational frequencies in SARS-CoV-2 genomes of Bangladesh: possible implications from the ongoing outbreak in Bangladesh
Author Otun Saha, Israt Islam, Rokaiya Nurani Shatadru, Nadira Naznin Rakhi, Md Shahadat Hossain
Evidence After completing all of the above screening processes, finally 198 unique SARS-CoV-2 genome sequences were selected for further mutational analyses and the metadata of all the studied 198 sequences are summarized in ST1.