Mutation detail:
Mutation site | N23S |
Virus | Norovirus |
Mutation level ![]() |
Amino acid level |
Gene/protein/region type | ORF3 |
Gene ID | 1491971 |
Country | China |
Mutation type ![]() |
nonsynonymous mutation |
Genotype/subtype/clade | GII.4 |
Sample ![]() |
Human |
Variants | - |
Viral reference sequence | JN595867.1 |
Drug/antibody/vaccine | - |
Transmissibility ![]() |
- |
Transmission mechanism | - |
Pathogenicity ![]() |
- |
Pathogenicity mechanism | - |
Immune escape mutation | - |
Immune escape mechanism | - |
RT-PCR primers probes | - |
Protein detail:
Protein name | Protein VP2 |
Uniprot protein ID | Q83885 |
Protein length | 212 amino acids |
Protein description | The ORF3 encodes the minor capsid protein VP2, minor structural protein present in one or two copies per virion. VP2 stabilizes capsid protein VP1 by protecting it from disassembly and degradation. VP2 may play a role in RNA genome packaging. |
Literature information:
Pubmed ID | 23824633 |
Clinical information | No |
Disease | - |
Published year | 2013 |
Journal | Virus Genes |
Title | Complete genome analysis of a novel norovirus GII.4 variant identified in China |
Author | Liang Xue, Qingping Wu, Xiaoxia Kou, Weicheng Cai, Jumei Zhang |
Evidence | Table 1 |