Mutation detail:
Mutation site | E769D |
Virus | Varicella-Zoster virus |
Mutation level ![]() |
Amino acid level |
Gene/protein/region type | ORF11 |
Gene ID | 1487654 |
Country | Canada |
Mutation type ![]() |
nonsynonymous mutation |
Genotype/subtype/clade | - |
Sample ![]() |
Human |
Variants | - |
Viral reference sequence | NC_001348.1 |
Drug/antibody/vaccine | - |
Transmissibility ![]() |
- |
Transmission mechanism | - |
Pathogenicity ![]() |
- |
Pathogenicity mechanism | - |
Immune escape mutation | - |
Immune escape mechanism | - |
RT-PCR primers probes | - |
Protein detail:
Protein name | Tegument Protein VP13/14 |
Uniprot protein ID | - |
Protein length | 819 amino acids |
Protein description | Tegument protein; required for normal levels of IE4, IE62, IE63 and gE; RNA-binding domain (amino acids 1-22); binding to ORF9 required for efficient virion assembly. |
Literature information:
Pubmed ID | 22837206 |
Clinical information | No |
Disease | - |
Published year | 2012 |
Journal | JOURNAL OF VIROLOGY |
Title | The Attenuated Genotype of Varicella-Zoster Virus Includes an ORF0 Transitional Stop Codon Mutation |
Author | Geoffrey A Peters,Shaun D Tyler,John E Carpenter,Wallen Jackson,Yasuko Mori |
Evidence | Table1 |