AVM v1, released 02-OCT-22

A manually curated database of aerosol-transmitted virus mutations, human diseases, and drugs

Mutation detail:


Mutation site N66H
Virus SARS-CoV-2
Mutation level Amino acid level
Gene/protein/region type E
Gene ID 43740570
Country -
Mutation type nonsynonymous mutation
Genotype/subtype/clade -
Sample Human
Variants -
Viral reference sequence MN908947.3
Drug/antibody/vaccine -
Transmissibility -
Transmission mechanism -
Pathogenicity -
Pathogenicity mechanism -
Immune escape mutation -
Immune escape mechanism -
RT-PCR primers probes -

Protein detail:


Protein name Envelope Protein
Uniprot protein ID P0DTC4
Protein length 75 amino acids
Protein description The SARS-CoV-2 envelope (E) protein is a small structural protein involved in many aspects of the viral life cycle. The E protein promotes the packaging and reproduction of the virus, and deletion of this protein weakens or even abolishes the virulence.

Literature information:


Pubmed ID 33239633
Clinical information No
Disease -
Published year 2020
Journal Nature Communications
Title No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2
Author Lucy van Dorp, Damien Richard, Cedric C S Tan, Liam P Shaw, Mislav Acman
Evidence Supplementary Data1