Mutation detail:
| Mutation site | P71S |
| Virus | SARS-CoV-2 |
Mutation level  |
Amino acid level |
| Gene/protein/region type | E |
| Gene ID | 43740570 |
| Country | - |
| Mutation type |
nonsynonymous mutation |
| Genotype/subtype/clade | - |
| Sample |
Human |
| Variants | - |
| Viral reference sequence | NC_045512.2 |
| Drug/antibody/vaccine | - |
| Transmissibility |
- |
| Transmission mechanism | - |
| Pathogenicity |
- |
| Pathogenicity mechanism | - |
| Immune escape mutation | - |
| Immune escape mechanism | - |
| RT-PCR primers probes | - |
Protein detail:
| Protein name | Envelope Protein |
| Uniprot protein ID | P0DTC4 |
| Protein length | 75 amino acids |
| Protein description | The SARS-CoV-2 envelope (E) protein is a small structural protein involved in many aspects of the viral life cycle. The E protein promotes the packaging and reproduction of the virus, and deletion of this protein weakens or even abolishes the virulence. |
Literature information:
| Pubmed ID | 34281387 |
| Clinical information | No |
| Disease | - |
| Published year | 2021 |
| Journal | mBio |
| Title | Evolutionary Tracking of SARS-CoV-2 Genetic Variants Highlights an Intricate Balance of Stabilizing and Destabilizing Mutations |
| Author | Jobin John Jacob, Karthick Vasudevan, Agila Kumari Pragasam, Karthik Gunasekaran, Balaji Veeraraghavan |
| Evidence | Mutation mapping showed a total of 106 amino acid substitutions (missense mutations in >5 genomes) from a representative set of 513 genomes. The analysis also revealed 36 mutations that were found in >5% of genome sequences, while 12 major substitutions were lineage-defining mutations (Fig. 1). |