AVM v1, released 02-OCT-22

A manually curated database of aerosol-transmitted virus mutations, human diseases, and drugs

Mutation detail:


Mutation site S23F
Virus SARS-CoV-2
Mutation level Amino acid level
Gene/protein/region type ORF10
Gene ID 43740576
Country China,USA,Australia,Spain
Mutation type nonsynonymous mutation
Genotype/subtype/clade -
Sample Human
Variants -
Viral reference sequence NC_045512.2
Drug/antibody/vaccine -
Transmissibility -
Transmission mechanism -
Pathogenicity -
Pathogenicity mechanism -
Immune escape mutation -
Immune escape mechanism -
RT-PCR primers probes -

Protein detail:


Protein name ORF10 protein
Uniprot protein ID -
Protein length 38 amino acids
Protein description ORF10 encodes a potential viral accessory protein.It is Coronavirus 3' UTR pseudoknot stem-loop.

Literature information:


Pubmed ID 33072702
Clinical information No
Disease -
Published year 2020
Journal Frontiers in Public Health
Title Epidemiological and Genomic Analysis of SARS-CoV-2 in 10 Patients From a Mid-Sized City Outside of Hubei, China in the Early Phase of the COVID-19 Outbreak
Author Jinkun Chen,Evann E.Hilt,Fan Li,Huan Wu,Zhuojing Jiang
Evidence We investigated each SNP to determine if there were any non-synonymous mutations in genes important to the virus lifecycle. Several non-synonymous mutations were found in the following genes: orf1ab, orf3, N, orf8, and orf10 (Table 4A).