Mutation detail:
| Mutation site | C1199Y |
| Virus | Human rhinovirus |
Mutation level  |
Amino acid level |
| Gene/protein/region type | VP1 |
| Gene ID | 1461213 |
| Country | - |
| Mutation type |
nonsynonymous mutation |
| Genotype/subtype/clade | B |
| Sample |
cell line |
| Variants | - |
| Viral reference sequence | NC_001490.1 |
| Drug/antibody/vaccine | - |
| Transmissibility |
- |
| Transmission mechanism | - |
| Pathogenicity |
- |
| Pathogenicity mechanism | - |
| Immune escape mutation | - |
| Immune escape mechanism | - |
| RT-PCR primers probes | - |
Protein detail:
| Protein name | Capsid Protein VP1 |
| Uniprot protein ID | P03303 |
| Protein length | 289 amino acids |
| Protein description | VP1 forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. Capsid protein VP1 mainly forms the vertices of the capsid. Capsid protein VP1 interacts with host ICAM1 to provide virion attachment to target host cells. |
Literature information:
| Pubmed ID | 9671723 |
| Clinical information | No |
| Disease | - |
| Published year | 1998 |
| Journal | Proceedings Of The National Academy Of Sciences Of The United States Of America |
| Title | Identification of viral mutants by mass spectrometry |
| Author | J K Lewis,M Bendahmane,T J Smith,R N Beachy,G Siuzdak |
| Evidence | Comparative mass mapping was applied to a structural protein of the human rhinovirus Cys1199 -->Tyr mutant |