AVM v1, released 02-OCT-22

A manually curated database of aerosol-transmitted virus mutations, human diseases, and drugs

Mutation detail:


Mutation site 94296A>G
Virus Varicella-Zoster virus
Mutation level Nucleotide level
Gene/protein/region type ORF54
Gene ID 1487723
Country -
Mutation type -
Genotype/subtype/clade -
Sample cell line
Variants -
Viral reference sequence NC_001348.1
Drug/antibody/vaccine -
Transmissibility -
Transmission mechanism -
Pathogenicity -
Pathogenicity mechanism -
Immune escape mutation -
Immune escape mechanism -
RT-PCR primers probes -

Protein detail:


Protein name Capsid Portal Protein
Uniprot protein ID P09302
Protein length 769 amino acids
Protein description Forms a portal in the viral capsid through which viral DNA is translocated during DNA packaging. Assembles as a dodecamer at a single fivefold axe of the T=16 icosahedric capsid. Binds to the molecular motor that translocates the viral DNA, termed terminase.

Literature information:


Pubmed ID 29242077
Clinical information No
Disease -
Published year 2017
Journal Virus Passaged in Cell Culture
Title Vaccine-Type Mutations Identified in Varicella Zoster Virus Passaged in Cell Culture
Author Seok Cheon Kim1 , Youn Hee Won1 , Ji Seon Park1 , Jeong Seon Jeon1 , Jin Hyun Ahn
Evidence Table3