Mutation detail:
| Mutation site | k68del |
| Virus | SARS-CoV-2 |
Mutation level  |
Amino acid level |
| Gene/protein/region type | ORF8 |
| Gene ID | 43740577 |
| Country | England |
| Mutation type |
nonsynonymous mutation |
| Genotype/subtype/clade | - |
| Sample |
Human |
| Variants | Alpha |
| Viral reference sequence | NC_045512.2 |
| Drug/antibody/vaccine | - |
| Transmissibility |
- |
| Transmission mechanism | - |
| Pathogenicity |
- |
| Pathogenicity mechanism | - |
| Immune escape mutation | - |
| Immune escape mechanism | - |
| RT-PCR primers probes | - |
Protein detail:
| Protein name | ORF8 protein |
| Uniprot protein ID | - |
| Protein length | 121 amino acids |
| Protein description | - |
Literature information:
| Pubmed ID | 33704818 |
| Clinical information | No |
| Disease | - |
| Published year | 2021 |
| Journal | JOURNAL OF MEDICAL VIROLOGY |
| Title | Immunoinformatic analysis of structural and epitope variations in the spike and Orf8 proteins of SARS-CoV-2/B.1.1.7 |
| Author | Mushtaq Hussain, Sanya Shabbir, Anusha Amanullah, Fozia Raza, Muhammad J Imdad |
| Evidence | Sequence alignment verified the existence of mutations in orf1a/b (T1001I, A1708D, I2230T, S2625X, and delSGF3675-3677), spike (delHV69-70, del144Y, N501Y, A570D, D614G, P681H, T716I, S982A, and D1118H), orf8 (Q27X, R52I, del68K, Y73C, L118V, F120L, and I121F) and N (D3L, R203K, G204R, and S235F) proteins in SARS-CoV-2/B.1.1.7 compared to the SARS-CoV-2/Wuhan (Figures 1 and S1-S5). |