Mutation detail:
Mutation site | 10906A>G |
Virus | Measles virus |
Mutation level ![]() |
Nucleotide Level |
Gene/protein/region type | L |
Gene ID | 1489802 |
Country | Japan |
Mutation type ![]() |
- |
Genotype/subtype/clade | - |
Sample ![]() |
Human |
Variants | - |
Viral reference sequence | S58435.1 |
Drug/antibody/vaccine | - |
Transmissibility ![]() |
- |
Transmission mechanism | - |
Pathogenicity ![]() |
- |
Pathogenicity mechanism | - |
Immune escape mutation | - |
Immune escape mechanism | - |
RT-PCR primers probes | - |
Protein detail:
Protein name | Large Polymerase Protein |
Uniprot protein ID | P12576 |
Protein length | 2183 amino acids |
Protein description | The viral polymerase (an RNA-dependent RNA polymerase, RdRp) or large protein is coded by the L gene. It catalyzes RNA synthesis, polymerization, capping, polymerization, methylation and polyadenylation. The negative sense RNA is transcribed directly into mRNA without forming any DNA intermediate. |
Literature information:
Pubmed ID | 9131467 |
Clinical information | No |
Disease | SSPE(Subacute sclerosing panencephalitis) |
Published year | 1997 |
Journal | JOURNAL OF MEDICAL VIROLOGY |
Title | Identification of three lineages of wild measles virus by nucleotide sequence analysis of N, P, M, F, and L genes in Japan |
Author | S Yamaguchi |
Evidence | Fig.3 |