Mutation detail:
| Mutation site | F58S |
| Virus | MERS-CoV |
| Mutation level |
Amino acid level |
| Gene/protein/region type | ORF3 |
| Gene ID | 14254595 |
| Country | - |
| Mutation type |
nonsynonymous mutation |
| Genotype/subtype/clade | - |
| Sample |
Human |
| Variants | - |
| Viral reference sequence | JX869059.2 |
| Drug/antibody/vaccine | - |
| Transmissibility |
- |
| Transmission mechanism | - |
| Pathogenicity |
- |
| Pathogenicity mechanism | - |
| Immune escape mutation | - |
| Immune escape mechanism | - |
| RT-PCR primers probes | - |
Protein detail:
| Protein name | ORF3 protein |
| Uniprot protein ID | K9N796 |
| Protein length | 103 amino acids |
| Protein description | - |
Literature information:
| Pubmed ID | 24055451 |
| Clinical information | No |
| Disease | - |
| Published year | 2013 |
| Journal | Lancet |
| Title | Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study |
| Author | Matthew Cotten,Simon J Watson,Paul Kellam,Abdullah A Al-Rabeeah,Hatem Q Makhdoom |
| Evidence | The EMC/2012 sequence was obtained after extensive cell culture passage to establish a virus isolate;26 there are 76 single nucleotide differences between EMC/2012 and the root of the clade B lineage.Figure 2 |