AVM v1, released 02-OCT-22

A manually curated database of aerosol-transmitted virus mutations, human diseases, and drugs

Mutation detail:


Mutation site 26313C>T
Virus SARS-CoV-2
Mutation level Nucleotide level
Gene/protein/region type E
Gene ID 43740570
Country Pakistan
Mutation type -
Genotype/subtype/clade -
Sample Human
Variants -
Viral reference sequence NC_045512.2
Drug/antibody/vaccine -
Transmissibility -
Transmission mechanism -
Pathogenicity -
Pathogenicity mechanism -
Immune escape mutation -
Immune escape mechanism -
RT-PCR primers probes -

Protein detail:


Protein name Envelope Protein
Uniprot protein ID P0DTC4
Protein length 75 amino acids
Protein description The SARS-CoV-2 envelope (E) protein is a small structural protein involved in many aspects of the viral life cycle. The E protein promotes the packaging and reproduction of the virus, and deletion of this protein weakens or even abolishes the virulence.

Literature information:


Pubmed ID 33755704
Clinical information No
Disease -
Published year 2021
Journal PLoS One
Title Whole-genome sequencing of SARS-CoV-2 reveals the detection of G614 variant in Pakistan
Author Massab Umair, Aamer Ikram, Muhammad Salman, Adnan Khurshid, Masroor Alam
Evidence Overall, twenty-nine amino acid mutations were detected in the current study genome sequences, including fifteen missense and four novel mutations. Table3