AVM v1, released 02-OCT-22

A manually curated database of aerosol-transmitted virus mutations, human diseases, and drugs

Mutation detail:


Mutation site 26424T>C
Virus SARS-CoV-2
Mutation level Nucleotide level
Gene/protein/region type E
Gene ID 43740570
Country -
Mutation type -
Genotype/subtype/clade -
Sample Human
Variants -
Viral reference sequence NC_045512.2
Drug/antibody/vaccine -
Transmissibility -
Transmission mechanism -
Pathogenicity -
Pathogenicity mechanism -
Immune escape mutation -
Immune escape mechanism -
RT-PCR primers probes -

Protein detail:


Protein name Envelope Protein
Uniprot protein ID P0DTC4
Protein length 75 amino acids
Protein description The SARS-CoV-2 envelope (E) protein is a small structural protein involved in many aspects of the viral life cycle. The E protein promotes the packaging and reproduction of the virus, and deletion of this protein weakens or even abolishes the virulence.

Literature information:


Pubmed ID 34121111
Clinical information No
Disease -
Published year 2021
Journal Briefings In Bioinformatics
Title Co-mutation modules capture the evolution and transmission patterns of SARS-CoV-2.
Author Luyao Qin,Xiao Ding,Yongjie Li,Qingfeng Chen,Jing Meng
Evidence We identified 26 459 nucleotide mutations from the 444 478 SARS-CoV-2 genomes, of which 168 nucleotide mutations were involved in the 474 co-mutation pairs and 42 co-mutation modules.