Mutation detail:
| Mutation site | I62N |
| Virus | Human rhinovirus |
Mutation level  |
Amino acid level |
| Gene/protein/region type | VP3 |
| Gene ID | 1493933 |
| Country | - |
| Mutation type |
nonsynonymous mutation |
| Genotype/subtype/clade | A |
| Sample |
Human |
| Variants | - |
| Viral reference sequence | NC_038311.1 |
| Drug/antibody/vaccine | Mab 806 resisitant |
| Transmissibility |
- |
| Transmission mechanism | - |
| Pathogenicity |
- |
| Pathogenicity mechanism | - |
| Immune escape mutation | Yes |
| Immune escape mechanism | - |
| RT-PCR primers probes | - |
Protein detail:
| Protein name | Capsid Protein VP3 |
| Uniprot protein ID | P07210 |
| Protein length | 238 amino acids |
| Protein description | Capsid Protein VP3 forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. |
Literature information:
| Pubmed ID | 8381460 |
| Clinical information | No |
| Disease | - |
| Published year | 1993 |
| Journal | Journal Of General Virology |
| Title | The nature and spatial distribution of amino acid substitutions conferring resistance to neutralizing monoclonal antibodies in human rhinovirus type 2 |
| Author | S A Speller,D V Sangar,B E Clarke,D J Rowlands |
| Evidence | Table 3 |