Mutation detail:
| Mutation site | 27800C>A |
| Virus | SARS-CoV-2 |
Mutation level  |
Nucleotide level |
| Gene/protein/region type | ORF7b |
| Gene ID | 43740574 |
| Country | - |
| Mutation type |
- |
| Genotype/subtype/clade | - |
| Sample |
Human |
| Variants | - |
| Viral reference sequence | NC_045512.2 |
| Drug/antibody/vaccine | - |
| Transmissibility |
- |
| Transmission mechanism | - |
| Pathogenicity |
- |
| Pathogenicity mechanism | - |
| Immune escape mutation | - |
| Immune escape mechanism | - |
| RT-PCR primers probes | - |
Protein detail:
| Protein name | ORF7b |
| Uniprot protein ID | - |
| Protein length | 43 amino acids |
| Protein description | ORF7b encodes a viral accessory protein. Based on its similarity to other coronavirus proteins, ORF7b protein is thought to localize to the Golgi compartment. The orf7b is a hydrophobic protein with a transmembrane domain N-terminal at the outside, and a cytoplasmic C-terminal. Similar to orf7a, orf7b is reported by the majority of the previous studies that it is not essential for virus replication. |
Literature information:
| Pubmed ID | 34121111 |
| Clinical information | No |
| Disease | - |
| Published year | 2021 |
| Journal | Briefings In Bioinformatics |
| Title | Co-mutation modules capture the evolution and transmission patterns of SARS-CoV-2. |
| Author | Luyao Qin,Xiao Ding,Yongjie Li,Qingfeng Chen,Jing Meng |
| Evidence | We identified 26 459 nucleotide mutations from the 444 478 SARS-CoV-2 genomes, of which 168 nucleotide mutations were involved in the 474 co-mutation pairs and 42 co-mutation modules. |