Mutation detail:
Protein detail:
| Protein name | ORF7b |
| Uniprot protein ID | - |
| Protein length | 43 amino acids |
| Protein description | ORF7b encodes a viral accessory protein. Based on its similarity to other coronavirus proteins, ORF7b protein is thought to localize to the Golgi compartment. The orf7b is a hydrophobic protein with a transmembrane domain N-terminal at the outside, and a cytoplasmic C-terminal. Similar to orf7a, orf7b is reported by the majority of the previous studies that it is not essential for virus replication. |
Literature information:
| Pubmed ID | 33705994 |
| Clinical information | No |
| Disease | - |
| Published year | 2021 |
| Journal | COMPUTERS IN BIOLOGY AND MEDICINE |
| Title | A hijack mechanism of Indian SARS-CoV-2 isolates for relapsing contemporary antiviral therapeutics |
| Author | R. Prathiviraj, S. Saranya, M. Bharathi, and P. Chellapandi |
| Evidence | Forty-one protein mutations were identified in 12 Indian SARS-CoV-2 isolates by analysis of genome variations across 460 genome sequences obtained from 30 geographic sites in India. Two unique mutations such as W6152R and N5928H found in exonuclease of Surat (GBRC275b) and Gandhinagar (GBRC239) isolates |